Correlation between low/high affinity ratios for 5-HT1A receptors and intrinsic activity
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference26 articles.
1. To what extend can binding studies allow the quantification of affinity and efficacy?;Birdsall;Ann. N. Y. Acad. Sci.,1997
2. S-14506 — a novel, potent, high-efficacy 5-HT1A agonist and potential anxiolytic agent;Colpaert;Drug Dev. Res.,1992
3. Physical evidence of the coupling of solubilized 5-HT1A binding sites with G regulatory proteins;Emerit;Biochem. Pharmacol.,1990
4. Effector coupling mechanisms of the cloned 5-HT1A receptor;Fargin;J. Biol. Chem.,1989
5. High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action;Fitzgerald;J. Neurochem.,1999
Cited by 34 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Different Alterations of Agonist and Antagonist Binding to 5-HT1A Receptor in a Rat Model of Parkinson’s Disease and Levodopa-Induced Dyskinesia: A MicroPET Study;Journal of Parkinson's Disease;2021-08-02
2. Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging;Current Medicinal Chemistry;2016-06-21
3. New Multi-target Antagonists of 1A-, 1D-Adrenoceptors and 5-HT1A Receptors Reduce Human Hyperplastic Prostate Cell Growth and the Increase of Intraurethral Pressure;Journal of Pharmacology and Experimental Therapeutics;2015-10-22
4. Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs;Biochemical Pharmacology;2015-05
5. Case Study 2;Blood-Brain Barrier in Drug Discovery;2015-01-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3