Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition
Author:
Funder
Kementerian Sains, Teknologi dan Inovasi
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00210-019-01651-0.pdf
Reference45 articles.
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3. Bapiro EB, Hasler JA, Ridderstrom M, Masimirembwa CM (2002) The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variant: potential implications for CYP2D6 phenotyping studies and the clinical use of CYP2D6 substrate drugs in some African populations. Biochem Pharmacol 64:1387–1398
4. Berka K, Paloncýová M, Anzenbacher P, Otyepka M (2013) Behavior of human cytochromes P450 on lipid membranes. J Phys Chem B 117:11556–11564
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