Functional analysis of CYP2D6.31 variant: Homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution-Reference-Cited by-同舟云学术

Functional analysis of CYP2D6.31 variant: Homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution

Published:2005-02-22 Issue:2 Volume:59 Page:339-346
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Allorge Delphine,Bréant Didier,Harlow Jacky,Chowdry Joey,Lo-Guidice Jean-Marc,Chevalier Dany,Cauffiez Christelle,Lhermitte Michel,Blaney Frank E.,Tucker Geoffrey T.,Broly Franck,Ellis S. Wynne

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

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5. A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine;Evert;Naunyn-Schmiedeberg's Arch Pharmacol,1994

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