Role of Nrf2/HO-1, PPAR-γ, and cytoglobin signals in the pathogenesis of methotrexate-induced testicular intoxication in rats and the protective effect of diacerein-Reference-Cited by-同舟云学术

Role of Nrf2/HO-1, PPAR-γ, and cytoglobin signals in the pathogenesis of methotrexate-induced testicular intoxication in rats and the protective effect of diacerein

Published:2023-12-07 Issue: Volume: Page:
ISSN:0028-1298
Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
language:en
Short-container-title:Naunyn-Schmiedeberg's Arch Pharmacol

Author:

Abdel-Reheim Mustafa Ahmed,Ali Gaber F.,Hassanein Emad H. M.,Mohamed Wafaa R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00210-023-02876-w.pdf

Reference83 articles.

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2. Abdel-Gaber SA, Mohammed RK, Refaie MM (2018) Mechanism mediating the protective effect of diacerein in ischemia-reperfusion-induced testicular injury in rats. Life Sci 209:57–62

3. Abd-Ellatif RN, Hegab II, Atef MM, Sadek MT, Hafez YM (2019) Diacerein protects against glycerol-induced acute kidney injury: modulating oxidative stress, inflammation, apoptosis and necroptosis. Chem Biol Interact 306:47–53

4. Abdelzaher W, Khalaf H, El-Hussieny M, Bayoumi A, Shehata S, Refaie M (2020) Role of nitric oxide donor in methotrexate-induced testicular injury via modulation of pro-inflammatory mediators, eNOS and P-glycoprotein. Hum Exp Toxicol 39:1700–1709

5. Ali FE, Bakr AG, Abo-Youssef AM, Azouz AA, Hemeida RA (2018) Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis. Life Sci 207:50–60