Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production-Reference-Cited by-同舟云学术

Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production

Published:2012-05-29 Issue:5 Volume:97 Page:1963-1971
ISSN:0175-7598
Container-title:Applied Microbiology and Biotechnology
language:en
Short-container-title:Appl Microbiol Biotechnol

Author:

Geng Feng,Chen Zhen,Zheng Ping,Sun Jibin,Zeng An-Ping

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s00253-012-4062-8.pdf

Reference30 articles.

1. Bearer CF, Neet KE (1978) Threonine inhibition of aspartokinase-homoserine dehydrogenase-I of Escherichia-coli—slow transient and cooperativity of inhibition of aspartokinase activity. Biochem 17:3523–3530. doi: 10.1021/bi00610a016

2. Becker J, Wittmann C (2012) Systems and synthetic metabolic engineering for amino acid production—the heartbeat of industrial strain development. Curr Opinion Biotechnol

3. Bittel DC, Shaver JM, Somers DA, Gengenbach BG (1996) Lysine accumulation in maize cell cultures transformed with a lysine-insensitive form of maize dihydrodipicolinate synthase. Theor Appl Genet 92:70–77

4. Blagova E, Levdikov V, Milioti N, Fogg MJ, Kalliomaa AK, Brannigan JA, Wilson KS, Wilkinson AJ (2006) Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 angstrom resolution. Proteins 62:297–301. doi: 10.1002/Prot.20684

5. Blickling S, Beisel HG, Bozic D, Knablein J, Laber B, Huber R (1997) Structure of dihydrodipicolinate synthase of Nicotiana sylvestris reveals novel quaternary structure. J Mol Biol 274:608–621

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mining unique cysteine synthetases and computational study on thoroughly eliminating feedback inhibition through tunnel engineering;Protein Science;2024-09-14

2. Reconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic l-threonine producing Corynebacterium glutamicum;Bioresources and Bioprocessing;2024-04-26

3. Engineering allosteric inhibition of homoserine dehydrogenase by semi-rational saturation mutagenesis screening;Frontiers in Bioengineering and Biotechnology;2024-01-03

4. Insight into de-regulation of amino acid feedback inhibition: a focus on structure analysis method;Microbial Cell Factories;2023-08-23

5. Design and application of artificial rare L-lysine codons in Corynebacterium glutamicum;Frontiers in Bioengineering and Biotechnology;2023-05-30