Newly emerging synthetic cannabinoid ADB-4en-PINACA: its identification and quantification in an authentic human hair sample by GC–MS/MS

Author:

Wang Yue,Han Lifeng,Yi Liye,Liu Jinlei,Qiu Shi,Gu Jie,Bai Huiru,Li Jun,Wurita Amin,Hasegawa KoutaroORCID

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry (medical),Toxicology,Pathology and Forensic Medicine

Reference16 articles.

1. European Monitoring Centre for Drugs and Drug Addiction, European drug report 2021 : trends and developments, Publications Office of the European Union, 2021. https://data.europa.eu/doi/10.2810/18539

2. NPS Discovery (2021) ADB-4en-PINACA. https://www.npsdiscovery.org/wp-content/uploads/2021/03/ADB4en-PINACA_030421_NMSLabs_Report.pdf. Accessed 30 Aug 2021

3. European Monitoring Centre for Drugs and Drug Addiction. Formal notification of N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(pent-4-en-1-yl)-1H-indazole-3-carboxamide (ADB-4en-PINACA) by Hungary as a new psychoactive substance under the terms of Regulation (EU) 2017/2101. 2021. EU-EWS-RCS-FN-2021-0013.

4. Pike E, Grafinger KE, Cannaert A, Ametovski A, Luo JL, Sparkes E, Cairns EA, Ellison R, Gerona R, Stove CP, Auwärter V, Banister SD (2021) Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays: part I-synthesis, analytical characterization, and binding affinity for human CB1 receptors. Drug Test Anal 13:1383–1401. https://doi.org/10.1002/dta.3037

5. Grafinger KE, Cannaert A, Ametovski A, Sparkes E, Cairns E, Banister SD, Auwärter V, Stove CP (2021) Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays-part II: structure activity relationship assessment via a β-arrestin recruitment assay. Drug Test Anal 13:1402–1411. https://doi.org/10.1002/dta.3035

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