Huntington’s disease: lessons from prion disorders

Author:

Alpaugh MelanieORCID,Cicchetti FrancescaORCID

Funder

Fonds de Recherche du Québec - Santé

Canadian Institutes of Health Research

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical),Neurology

Reference137 articles.

1. Babcock DT, Ganetzky B (2015) Transcellular spreading of huntingtin aggregates in the Drosophila brain. PNAS 112(39):E5427–E5433. https://doi.org/10.1073/pnas.1516217112

2. Masnata M, Sciacca G, Maxan A, Bousset L, Denis HL, Lauruol F, David L, Saint-Pierre M, Kordower JH, Melki R, Alpaugh M, Cicchetti F (2019) Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms. Acta Neuropathol 137(6):981–1001. https://doi.org/10.1007/s00401-019-01973-6

3. Gosset P, Maxan A, Alpaugh M, Breger L, Dehay B, Tao Z, Ling Z, Qin C, Cisbani G, Fortin N, Vonsattel JG, Lacroix S, Oueslati A, Bezard E, Cicchetti F (2020) Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates. Neurobiol Dis 141:104941. https://doi.org/10.1016/j.nbd.2020.104941

4. Rieux M, Alpaugh M, Sciacca G, Saint-Pierre M, Masnata M, Denis HL, Levesque SA, Herrmann F, Bazenet C, Garneau AP, Isenring P, Truant R, Oueslati A, Gould PV, Ast A, Wanker EE, Lacroix S, Cicchetti F (2020) Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology. Mol Psychiatry. Epub ahead of print. https://doi.org/10.1038/s41380-020-0787-4. Erratum in: Mol Psychiatry. 2020 Jul 24: PMID: 32514103

5. Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, Lee N, Li L, Im W, Kim M, Kim HS, Oh SH, Kim TA, Ko JJ, Aube B, Oueslati A, Kim YJ, Song J (2016) Human-to-mouse prion-like propagation of mutant huntingtin protein. Acta Neuropathol 132(4):577–592. https://doi.org/10.1007/s00401-016-1582-9

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