Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance-Reference-Cited by-同舟云学术

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Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance

Published:2021-10-28 Issue: Volume: Page:
ISSN:1359-4184
Container-title:Molecular Psychiatry
language:en
Short-container-title:Mol Psychiatry

Author:

Alpaugh Melanie^ORCID,Denis Hélèna L.^ORCID,Cicchetti Francesca^ORCID

Funder

Fonds de Recherche du Québec - Santé

Gouvernement du Canada | Canadian Institutes of Health Research

Huntington’s Disease Society of America

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology

Link

https://www.nature.com/articles/s41380-021-01350-4.pdf

Reference101 articles.

1. Venkatraman P, Wetzel R, Tanaka M, Nukina N, Goldberg AL. Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol Cell. 2004;14:95–104.

2. Jana NR, Zemskov EA, Wang G, Nukina N. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release. Hum Mol Genet. 2001;10:1049–59.

3. Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell. 1997;90:537–48.

4. Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, et al. Human-to-mouse prion-like propagation of mutant huntingtin protein. Acta Neuropathol. 2016;132:577–92.

5. Wild EJ, Boggio R, Langbehn D, Robertson N, Haider S, Miller JR, et al. Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients. J Clin Investig. 2015;125:1979–86.

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1. Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins;Proceedings of the National Academy of Sciences;2024-07-29

2. Neuroimaging to Facilitate Clinical Trials in Huntington’s Disease: Current Opinion from the EHDN Imaging Working Group;Journal of Huntington's Disease;2024-07-02

3. Brain–Periphery Interactions in Huntington’s Disease: Mediators and Lifestyle Interventions;International Journal of Molecular Sciences;2024-04-25

4. Transmission-selective muscle pathology induced by the active propagation of mutant huntingtin across the human neuromuscular synapse;Frontiers in Molecular Neuroscience;2024-01-03

5. The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells;Saudi Pharmaceutical Journal;2023-12

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