Two flavone C-glycosides as quality control markers for the manufacturing process of ephedrine alkaloids-free Ephedra Herb extract (EFE) as a crude drug preparation

Author:

Oshima Naohiro,Maruyama Takuro,Yamashita Tadatoshi,Uchiyama Nahoko,Amakura Yoshiaki,Hyuga Sumiko,Hyuga Masashi,Nakamori Shunsuke,Takemoto Hiroaki,Kobayashi Yoshinori,Hakamatsuka Takashi,Odaguchi Hiroshi,Hanawa Toshihiko,Goda Yukihiro

Funder

Japan Agency for Medical Research and Development

Publisher

Springer Science and Business Media LLC

Subject

Molecular Medicine

Reference9 articles.

1. The Ministry of Health, Labour and Welfare of Japan (2016) The Japanese pharmacopoeia, 17th edn. The Ministry of Health, Labour and Welfare of Japan, Tokyo, pp 2515–2516

2. Hyuga S, Shiraishi M, Hyuga M, Goda Y, Hanawa T (2011) Ephedrae herba, a major component of maoto, inhibits the HGF-induced motility of human breast cancer MDA-MB-231 cells through suppression of c-Met tyrosine phosphorylation and c-Met expression. J Trad Med 28:128–138

3. Amakura Y, Yoshimura M, Yamakami S, Yoshida T, Wakana D, Hyuga M, Hyuga S, Hanawa T, Goda Y (2013) Characterization of phenolic constituents from Ephedra Herb extract. Molecules 18:5326–5334

4. Hyuga S, Hyuga M, Yoshimura M, Amakura Y, Goda Y, Hanawa T (2013) Herbacetin, a constituent of Ephedra herba, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. Planta Med 79:1525–1530

5. Hanawa T, Hyuga S, Aida Y, Hyuga M, Amakura Y, Yoshimura M (2014) Multikinase inhibitors containing flavonoids or their glycosides as anticancer drugs, analgesics, and antipruritic drugs. Jpn Kokai Tokkyo Koho, JP2014129341

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