Potentiation of the chemotherapeutic action of 5?-deoxy-5-fluorouridine in combination with guanosine and related compounds

Author:

Iigo Masaaki,Miwa Masanori,Ishitsuka Hideo,Nitta Kazuo

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference27 articles.

1. Arakawa M, Shimizu F, Sasagawa K, Inomata T, Shinkai K (1981) Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl-?-D-glucopyranosid) uronate against various experimental tumours. Gann 72:220?225

2. Ardalan B, Cooney DA, Jayaram HN, Carrico CK, Glazer RI, MacDonald J, Schein PS (1980) Mechanisms of sensitivity and resistance of murine tumors to 5-fluorouracil. Cancer Res 40:1431?1437

3. Armstrong RD, Diasio RB (1980) Metabolism and biological activity of 5?-deoxy-5-fluorouridine, a novel fluoropyrimidine. Cancer Res 40:3333?3338

4. Armstrong RD, Diasio RB (1981) Selective activation of 5?-deoxy-5-fluorouridine by tumor cells as a basis for an improved therapeutic index. Cancer Res 41:4891?4894

5. Au J L-S, Rustum YM, Minowada J, Srivastava BIS (1983) Differential selectivity of 5-fluorouracil and 5?-deoxy-5-fluorouridine in cultured human B lymphocytes and mouse L1210 leukemia. Biochem Pharmacol 32:541?546

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