IS2-mediated re-arrangement of the promoter sequence suppresses metabolic burden of the recombinant plasmid
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Microbiology
Link
http://link.springer.com/content/pdf/10.1007/BF02931406.pdf
Reference36 articles.
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3. Busby S., Ebright R.H.: Promoter structure, promoter recognition and transcription activation in prokaryotes.Cell 79, 743–746 (1994).
4. Camarena L., Poggio S., Campos A., Bastarrachea F., Osorio A.: An IS4 insertion at theglnA control region ofEscherichia coli creates a new promoter by providing the −35 region of its 3′-end.Plasmid 39, 41–47 (1998).
5. Chou C.F., Kuo B.Y., Lin W.J.: Optimization of the host-vector system and culture conditions for production of penicillin acylase inEscherichia coli.J.Biosci.Bioeng. 88, 160–167 (1999).
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1. Evaluating metabolic stress and plasmid stability in plasmid DNA production by Escherichia coli;Biotechnology Advances;2012-05
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