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Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies

  • Published:2019-01-02 Issue:3 Volume:49 Page:327-339
  • ISSN:0001-8244
  • Container-title:Behavior Genetics
  • language:en
  • Short-container-title:Behav Genet

Author:

Moen Gunn-HelenORCID,Hemani Gibran,Warrington Nicole M.,Evans David M.

Funder

Helse Sør-Øst RHF

National Health and Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Ecology, Evolution, Behavior and Systematics

Reference29 articles.

1. Bates TC, Maher BS, Medland SE, McAloney K, Wright MJ, Hansell NK, Kendler KS, Martin NG, Gillespie NA (2018) The nature of nurture: using a virtual-parent design to test parenting effects on children’s educational attainment in genotyped families. Twin Res Hum Genet 21(2):73–83

2. Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Moller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga JJ, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Zhang G, Ang W, Berry DJ, Bouchard L, Das S, Hakonarson H, Heikkinen J, Helgeland O, Hocher B, Hofman A, Inskip HM, Jones SE, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray A, Murray JC, Njolstad PR, Nohr EA, Reichetzeder C, Ring SM, Ruth KS, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Tuke MA, Vaudel M, Weedon MN, Willemsen G, Wood AR, Yaghootkar H, Muglia LJ, Bartels M, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Jarvelin MR, Bisgaard H, Grant SFA, Sorensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Frayling TM, Hivert MF, Felix JF, Hypponen E, Lowe WL Jr, Evans DM, Lawlor DA, Feenstra B, Freathy RM (2018) Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet 27(4):742–756

3. Boker S, Neale M, Maes H, Wilde M, Spiegel M, Brick T, Spies J, Estabrook R, Kenny S, Bates T, Mehta P, Fox J (2011) OpenMx: an open source extended structural equation modeling framework. Psychometrika 76(2):306–317

4. Boyd A, Golding J, Macleod J, Lawlor DA, Fraser A, Henderson J, Molloy L, Ness A, Ring S, Davey Smith G (2013) Cohort Profile: the ‘children of the 90s’--the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol 42(1):111–127

5. Eaves LJ, Pourcain BS, Smith GD, York TP, Evans DM (2014) Resolving the effects of maternal and offspring genotype on dyadic outcomes in genome wide complex trait analysis (“M-GCTA”). Behav Genet 44(5):445–455
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