Pharmacokinetics and biochemical efficacy after single and multiple oral administration of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a new type of specific competitive inhibitor of testosterone 5α-reductase, in volunteers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/BF03189869.pdf
Reference13 articles.
1. Rasmusson G.H., Reynolds G.F., Utne T., et al. (1984): Azasteroids as inhibitors of rat prostatic Sa-reductase. J. Med. Chem., 27, 1690–1701.
2. Liang T., Cascieri M.A., Cheung A.H., Reynolds G.F., Rasmusson G.H. (1985): Species difference in prostatic steroids 5α-reductases of rat, dog and human. Endocrinology, 117, 571–579.
3. Brooks J.R., Berman C., Primka R.L., Reynolds G.F., Rasmusson G.H. (1986): 5α-Reductase inhibitory and anti-androgenic activities of some 4-azasteroids in the rat. Steroids, 47, 1–19.
4. Brooks J.R., Baptiska E.M., Berman C., et al. (1981): Response of rat ventral prostate to a new and novel 5α-reductase inhibitor. Endocrinology, 109, 830–836.
5. Wenderoth U.K., George F.W., Wilson J.D. (1983): The effect of a 5α-reductase inhibitor on androgen-mediated growth of the dog prostate. Endocrinology, 113, 569–573.
Cited by 57 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetic, Pharmacodynamic, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia;Advances in Therapy;2024-06-04
2. A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function;Journal of Pharmaceutical Investigation;2023-10-30
3. Chance Favors the Perplexed Mind: The Critical Role of Mechanistic Biochemistry in Drug Discovery;Biochemistry;2021-07-14
4. 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence;Bladder Cancer;2020-12-14
5. Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date;Drug Design, Development and Therapy;2020-03
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3