Carnitine palmitoyltransferase in the heart is controlled by a different mechanism than the hepatic enzyme
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Clinical Biochemistry,Molecular Biology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF01270567.pdf
Reference12 articles.
1. McGarry JD, Foster DW: Regulation of hepatic fatty acid oxidation and ketone body production. Annu Rev Biochem 49: 395?420, 1980
2. Cook GA, Otto DA, Cornell NW: Differential inhibition of ketogenesis by malonyl-CoA in mitochondria from fed and starved rats. Biochem J 192: 955?958, 1980
3. Cook GA: Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in K; values. J Biol Chem 259: 12030?12033, 1984
4. Cook GA, Gamble MS: Regulation of carnitine palmitoyltransferase by insulin results in decreased activity and decreased apparent K; values for malonyl-CoA. J Biol Chem 262: 2050?2055, 1987
5. Paulson DJ, Ward KM, Shug AL: Malonyl-CoA inhibition of carnitine palmitoyltransferase in rat heart mitochondria. FEBS Lett 176: 381?384, 1984
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