Pharmacokinetics of isotretinoin and its major blood metabolite following a single oral dose to man

Author:

Colburn W. A.,Vane F. M.,Shorter H. J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference7 articles.

1. Vane FM, Bugge CJL (1981) Identification of 4-oxo-13-cis-retinoic acid as the major metabolite of 13-cis-retinoic acid in human blood. Drug Metab Dispos 9: 515?520

2. Sporn MB, Dunlop NM, Newton DL, Smith JM (1976) Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed Proc 35: 1332?1338

3. Editorial comment: Vitamin A acid cancer prophylaxis (1976) Brit Med J 2: 2?3

4. Sporn MB, Newton DC (1979) Chemoprevention of cancer with retinoids. Fed Proc 38 [11]: 2528?2534

5. Khoo K-C, Reik FD, Colburn WA (1982) Pharmacokinetic profile of isotretinoin following a single oral dose of normal man. J Clin Pharmacol 22: 395?402

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