Identification and Utilization of Donor and Recipient Genetic Variants to Predict Survival After HCT: Are We Ready for Primetime?-Reference-Cited by-同舟云学术

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Identification and Utilization of Donor and Recipient Genetic Variants to Predict Survival After HCT: Are We Ready for Primetime?

Published:2015-02-21 Issue:1 Volume:10 Page:45-58
ISSN:1558-8211
Container-title:Current Hematologic Malignancy Reports
language:en
Short-container-title:Curr Hematol Malig Rep

Author:

Sucheston-Campbell Lara E.,Clay Alyssa,McCarthy Philip L.,Zhu Qianqian,Preus Leah,Pasquini Marcelo,Onel Kenan,Hahn Theresa

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Hematology

Link

http://link.springer.com/content/pdf/10.1007/s11899-014-0246-x.pdf

Reference102 articles.

1. Spellman S, Setterholm M, Maiers M, Noreen H, Oudshoorn M, Fernandez-Vina M, et al. Advances in the selection of HLA-compatible donors: refinements in HLA typing and matching over the first 20 years of the National Marrow Donor Program Registry. Biol Blood Marrow Transplant J Am Soc Blood Marrow Transplant. 2008;14(9 Suppl):37–44. doi: 10.1016/j.bbmt.2008.05.001 .

2. Hahn T, McCarthy Jr PL, Hassebroek A, Bredeson C, Gajewski JL, Hale GA, et al. Significant improvement in survival after allogeneic hematopoietic cell transplantation during a period of significantly increased use, older recipient age, and use of unrelated donors. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(19):2437–49. doi: 10.1200/JCO.2012.46.6193 . This study describes changes in allogeneic HCT use, technique and survival in over 38,000 patients over 12 years. The data show that over time, use of unrelated donor HCTs has increased in an older patient population with significant improvements in survival after HCT. These data provide a good argument for continuing to pursue non-HLA matching to further improve survival after URD-HCT.

3. Majhail NS, Chitphakdithai P, Logan B, King R, Devine S, Rossmann SN et al. Significant improvement in survival after unrelated donor hematopoietic cell transplantation in the recent era. Biol Blood Marrow Transplant. doi: 10.1016/j.bbmt.2014.10.001 .

4. Lee SJ, Klein J, Haagenson M, Baxter-Lowe LA, Confer DL, Eapen M, et al. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood. 2007;110(13):4576–83. doi: 10.1182/blood-2007-06-097386 .

5. Boyle AP, Hong EL, Hariharan M, Cheng Y, Schaub MA, Kasowski M, et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 2012;22(9):1790–7. doi: 10.1101/gr.137323.112 .

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation;EClinicalMedicine;2021-10

2. Pre-HCT mosaicism increases relapse risk and lowers survival in acute lymphoblastic leukemia patients post–unrelated HCT;Blood Advances;2021-01-05

3. Validation of genetic associations with acute GVHD and nonrelapse mortality in DISCOVeRY-BMT;Blood Advances;2019-08-07

4. Integrating somatic variant data and biomarkers for germline variant classification in cancer predisposition genes;Human Mutation;2018-10-11

5. Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation;Leukemia;2018-08-08

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