Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype-Reference-Cited by-同舟云学术

Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype

Published:2020-05-28 Issue:7-8 Volume:25 Page:535-547
ISSN:1360-8185
Container-title:Apoptosis
language:en
Short-container-title:Apoptosis

Author:

Zhong Boya,Shingyoji Masato,Hanazono Michiko,Nguyễn Thi Thanh,Morinaga Takao,Tada Yuji,Shimada Hideaki,Hiroshima Kenzo,Tagawa Masatoshi

Funder

Japan Society for the Promotion of Science

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry, medical,Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s10495-020-01612-6.pdf

Reference29 articles.

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3. Guo G, Chmielecki J, Goparaju C et al (2015) Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. Cancer Res 75:264–269

4. Bueno R, Stawiski EW, Goldstein LD et al (2016) Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations. Nat Genet 48:407–416

5. Shen J, Cao B, Wang Y et al (2018) Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer. J Exp Clin Cancer Res 37:175. https://doi.org/10.1186/s13046-018-0850-z

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