Advancements in MDM2 inhibition: Clinical and pre-clinical investigations of combination therapeutic regimens
Author:
Funder
Deanship of Scientific Research, Imam Mohammed Ibn Saud Islamic University
Publisher
Elsevier BV
Subject
Pharmaceutical Science,Pharmacology
Reference133 articles.
1. Co-targeting of MDM2 and CDK4/6 with siremadlin and ribociclib for the treatment of patients with well-differentiated or dedifferentiated liposarcoma: results from a proof-of-concept;Abdul Razak;Phase Ib Study. Clin. Cancer Res.,2022
2. Targeted MDM2 degradation reveals a new vulnerability for p53-inactivated triple-negative breast cancer;Adams;Cancer Discov.,2023
3. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1;Ambrosini;Oncogene,2007
4. Results of the phase I trial of RG7112, a small-molecule MDM2 antagonist in leukemia;Andreeff;Clin. Cancer Res.,2016
5. TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer;Araki;J. Clin. Invest.,2010
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. FLT3-PROTACs for combating AML resistance: Analytical overview on chimeric agents developed, challenges, and future perspectives;European Journal of Medicinal Chemistry;2024-11
2. Strategic advancement of E3 ubiquitin ligase in the management of hepatocellular carcinoma;Medical Oncology;2024-06-18
3. An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy;European Journal of Medicinal Chemistry;2024-06
4. p53/MDM2 signaling pathway in aging, senescence and tumorigenesis;Seminars in Cancer Biology;2024-06
5. Novel Approaches for Upregulation of Tumor Suppressor Proteins: Pioneering Strategies and Integrative Potentials;ACS Medicinal Chemistry Letters;2024-05-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3