The protective Th1 response in mice is induced in the T-cell zone only three weeks after infection with Leishmania major and not during early T-cell activation

Author:

Barthelmann Julia,Nietsch Julia,Blessenohl Maike,Laskay Tamas,van Zandbergen Ger,Westermann Jürgen,Kalies Kathrin

Publisher

Springer Science and Business Media LLC

Subject

Microbiology (medical),Immunology,General Medicine,Immunology and Allergy

Reference36 articles.

1. Sacks D, Noben-Trauth N (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2:845–858

2. Scott P, Artis D, Uzonna J, Zaph C (2004) The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development. Immunol Rev 201:318–338

3. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL (1986) Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136:2348–2357

4. Moll H, Rollinghoff M (1990) Resistance to murine cutaneous leishmaniasis is mediated by TH1 cells, but disease-promoting CD4 + cells are different from TH2 cells. Eur J Immunol 20:2067–2074

5. Scott P (1991) IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J Immunol 147:3149–3155

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