Delivering Small Interfering RNA for Novel Therapeutics

Author:

Lu Patrick Y.,Woodle Martin C.

Publisher

Humana Press

Reference59 articles.

1. 1. Dykxhoorn, D.M. et al. (2005). Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol. 4, 457–467.

2. 2. Lu, P.Y. et al. (2003). siRNA-mediated antitumorigenesis for drug target validation and therapeutics. Curr Opin Mol Ther. 5, 225–234.

3. 3. Lu, P.Y. et al. (2005). In vivo application of RNA interference: from functional genomics to therapeutics. Adv Genet. 54:117–142.

4. 4. Xie, F.Y. et al. (2004). Delivering siRNA to animal disease models for validation of novel drug targets in vivo. PharmaGenomics, July/August, 28–38.

5. 5. Kim, B. et al. (2004). Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol. 165, 2177–2185.

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