A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tumors-Reference-Cited by-同舟云学术

A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tumors

Published:2015-12-01 Issue:1 Volume:34 Page:84-95
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Amin Manik,Minton Susan E.,LoRusso Patricia M.,Krishnamurthi Smitha S.,Pickett Cheryl A.,Lunceford Jared,Hille Darcy,Mauro David,Stein Mark N.,Wang-Gillam Andrea,Trull Lauren,Lockhart A. Craig

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-015-0306-7.pdf

Reference23 articles.

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3. Katayama H, Brinkley WR, Sen S (2003) The Aurora kinases: role in cell transformation and tumorigenesis. Cancer Metastasis Rev 22:451–464

4. Mountzios G, Terpos E, Dimopoulos MA (2008) Aurora kinases as targets for cancer therapy. Cancer Treat Rev 34:175–182

5. Lee W, Patel JH, Lockhart AC (2009) Novel targets in esophageal and gastric cancer: beyond antiangiogenesis. Expert Opin Investig Drugs 18:1351–1364

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