MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis-Reference-Cited by-同舟云学术

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MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis

Published:2010-04-16 Issue:5 Volume:29 Page:846-852
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Jasinski Piotr,Zwolak Pawel,Isaksson Vogel Rachel,Bodempudi Vidya,Terai Kaoru,Galvez Jorge,Land David,Dudek Arkadiusz Z.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-010-9432-4.pdf

Reference14 articles.

1. Galvez J, Garcia-Domenech R, de Julian-Ortiz JV, Soler R (1995) Topological approach to drug design. J Chem Inf Comput sci 35(2):272–84

2. Garcia-Domenech R, Galvez J, de Julian-Ortiz JV, Pogliani L (2008) Some new trends in chemical graph theory. Chem Rev 108(3):1127–69

3. Llompart J, Galvez J, Pal K (2006) Inventors; US Patent 20060014770

4. Jasinski P, Zwolak P, Terai K, Dudek AZ (2008) Novel Ras pathway inhibitor induces apoptosis and growth inhibition of K-ras-mutated cancer cells in vitro and in vivo. Transl Res 152(5):203–12

5. Jasinski P, Welsh B, Galvez J et al (2008) A novel quinoline, MT477: suppresses cell signaling through Ras molecular pathway, inhibits PKC activity, and demonstrates in vivo anti-tumor activity against human carcinoma cell lines. Invest New Drugs 26(3):223–32

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