Acute myeloid leukemia patients with NUP98::NSD1 showing initially poor treatment response can benefit from FLT3 inhibitors and venetoclax as well as HSCT-Reference-Cited by-同舟云学术

Acute myeloid leukemia patients with NUP98::NSD1 showing initially poor treatment response can benefit from FLT3 inhibitors and venetoclax as well as HSCT

Published:2022-11-24 Issue:2 Volume:102 Page:473-475
ISSN:0939-5555
Container-title:Annals of Hematology
language:en
Short-container-title:Ann Hematol

Author:

Sun Haimin,Yan Han,Yan Zeying,Zhu Yongmei,Yang Guang,Zhang Sujiang^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00277-022-05047-8.pdf

Reference9 articles.

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2. Dohner H, Wei AH, Appelbaum FR et al (2022) Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood 140(12):1345–1377. https://doi.org/10.1182/blood.2022016867

3. Khoury JD, Solary E, Abla O et al (2022) The 5th edition of the World Health Organization classification of haematolymphoid tumours: myeloid and histiocytic/dendritic neoplasms. Leukemia 36(7):1703–1719. https://doi.org/10.1038/s41375-022-01613-1

4. Hollink IH, van den Heuvel-Eibrink MM, Arentsen-Peters ST et al (2011) NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern. Blood 118(13):3645–3656. https://doi.org/10.1182/blood-2011-04-346643

5. Michmerhuizen NL, Klco JM, Mullighan CG (2020) Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies. Blood 136(20):2275–2289. https://doi.org/10.1182/blood.2020007093

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3. Novel ZFPL1::NUP98 fusion gene identified in an adult acute myeloid leukemia patient;International Journal of Laboratory Hematology;2024-02-06

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5. Allogeneic hematopoietic stem cell transplantation for adult acute myeloid leukemia patients with nucleoporin 98 (NUP98) gene rearrangements: A real-world study in China;2023-06-26