Development of Effective Siglec-9 Antibodies Against Cancer

Author:

Wang Jun Hui Shawn,Jiang Nan,Jain Amit,Lim JackweeORCID

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference59 articles.

1. Angata T, Varki A. Cloning, characterization, and phylogenetic analysis of Siglec-9, a new member of the CD33-related group of Siglecs: evidence for co-evolution with sialic acid synthesis pathways. J Biol Chem. 2000;275:22127–35.

2. Zhang JQ, Nicoll G, Jones C, Crocker PR. Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes. J Biol Chem. 2000;275:22121–6.

3. Avril T, Floyd H, Lopez F, Vivier E, Crocker PR. The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells. J Immunol Am Assoc Immunol. 2004;173:6841–9.

4. Jandus C, Boligan KF, Chijioke O, Liu H, Dahlhaus M, Démoulins T, et al. Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J Clin Inv Am Soc Clin Inv. 2014;124:1810–20.

5. Lizcano A, Secundino I, Dohrmann S, Corriden R, Rohena C, Diaz S, et al. Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation. Blood Am Soc Hematol. 2017;129:3100–10.

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