Development of IGF-IR inhibitors in pediatric sarcomas

Author:

Kolb E. Anders,Gorlick Richard

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference50 articles.

1. Jones JI, Clemmons DR: Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995, 16:3–34.

2. Rikhof B, de Jong S, Suurmeijer AJ, et al.: The insulin-like growth factor system and sarcomas. J Pathol 2009, 217:469–482.

3. Hermanto U, Zong CS, Wang LH: Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor I-mediated mitogen-activated protein kinase activation. Cell Growth Differ 2000, 11:655–664.

4. Kurmasheva RT, Houghton PJ: IGF-I mediated survival pathways in normal and malignant cells. Biochim Biophys Acta 2006, 1766:1–22.

5. Samani AA, Yakar S, LeRoith D, Brodt P: The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007, 28:20–47.

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