Evaluation of drug candidates: Efficacy readouts during lead optimization
Author:
Publisher
Birkhäuser-Verlag
Link
http://link.springer.com/content/pdf/10.1007/3-7643-7426-8_6.pdf
Reference264 articles.
1. Wohnsland F, Faller B (2001) High-throughput permeability pH profile and highthroughput alkane/water log P with artificial membranes. J Med Chem 44: 923–930
2. Phelps ME (2004) PET: molecular imaging and its biological applications. Springer, New York
3. Rudin M (2005) Molecular imaging — Basic principles and applications to biomedical research. Imperial College Press (London)
4. Jiang Q, Chopp M, Zhang AG, Knight RA, Jacobs N, Windham JP, Peck D, Ewing JR, Welch KMA (1997) The temporal evolution of MRI tissue signatures after transient middle cerebral artery occlusion in rat. J Neurol Sci 145: 15–23
5. Rudin M, Baumann D, Ekatodramis D, Stirnimann R, McAllister KH, Sauter A (2001) MRI analysis of the changes in apparanet water diffusion coefficient, T2 relaxation time, and cerebral blood flow and volume in the temporal evolution o cerebral infarction following permanent middle cerebral artery occlusion in rats. Exp Neurol 169: 56–63
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Imaging as a Localized Biomarker;Biomarkers in Drug Discovery and Development;2020-03-17
2. TB Drug Discovery from Target Identification to Proof of Concept Studies;Handbook of Tuberculosis;2017-09-18
3. An application of CIFAP for predicting the binding affinity of Chk1 inhibitors derived from 2-aminothiazole-4-carboxamide;Journal of Molecular Recognition;2017-06-16
4. Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs;Biotechnology Journal;2016-12-14
5. The CRE Luc Mouse Model for Bioimaging Ligand Activation of G Protein-Coupled Receptors;Methods in Pharmacology and Toxicology;2013-12-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3