Individual effect of shear rate and oxygen transfer on clavulanic acid production by Streptomyces clavuligerus
Author:
Funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Bioengineering,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s00449-021-02555-1.pdf
Reference44 articles.
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2. Paradkar AS, Aidoo KA, Jensen SE (1998) A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus. Mol Microbiol 27(4):831–843
3. Liu HB, Chui KS, Chan CL, Tsang CW, Leung YC (2004) An efficient heat-inducible Bacillus subtilis bacteriophage phi 105 expression and secretion system for the production of the Streptomyces clavuligerus beta-lactamase inhibitory protein (BLIP). J Biotechnol 108(3):207–217
4. Neves AA, Vieira LM, Menezes JC (2001) Effects of preculture variability on clavulanic acid fermentation. Biotechnol Bioeng 72(6):628–633
5. Higgens CE, Kastner RE (1971) Streptomyces clavuligerus sp. Nov., a β-lactam antibiotic producer. Int J Syst Evol Microbiol 21(4):326–331
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