Influence of dissolved oxygen and shear conditions on clavulanic acid production by Streptomyces clavuligerus
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Bioengineering,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s00449-004-0386-9.pdf
Reference20 articles.
1. Mayer AF, Deckwer W-D (1996) Simultaneous production and decomposition of clavulanic acid during Streptomyces clavuligerus cultivations. Appl Microbiol Biotechnol 45:41–46
2. Belmar-Beiny MT, Thomas CR (1991) Morphology and clavulanic acid production of Streptomyces clavuligerus: effect of stirrer speed in batch fermentations. Biotechnol Bioeng 37:456–462
3. Gavrilescu M, Roman RV, Efimov V (1993) The volumetric oxygen mass transfer coefficient in antibiotic biosynthesis liquids. Acta Biotechnol 13:59–70
4. Smith JJ, Lilly MD, Fox RI (1990) The effect of agitation on the morphology and penicillin production of Penicillium chrysogenum. Biotechnol Bioeng 35:1011–1023
5. Yegneswaran PK, Gray MR, Westlake DWS (1988) Effects of reduced oxygen on growth and antibiotic production in Streptomyces clavuligerus. Biotechnol Lett 10:479–484
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