Integrating Forward and Reverse Translation in PBPK Modeling to Predict Food Effect on Oral Absorption of Weakly Basic Drugs-Reference-Cited by-同舟云学术

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Integrating Forward and Reverse Translation in PBPK Modeling to Predict Food Effect on Oral Absorption of Weakly Basic Drugs

Published:2023-02 Issue:2 Volume:40 Page:405-418
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Franco Yesenia L.,Da Silva Lais,Charbe Nitin,Kinvig Hannah,Kim Soyoung,Cristofoletti Rodrigo

Funder

Simulations Plus

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s11095-023-03478-0.pdf

Reference58 articles.

1. Chen Y, Jin JY, Mukadam S, Malhi V, Kenny JR. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies. Biopharm Drug Dispos. 2012;33(2):85–98. https://doi.org/10.1002/bdd.1769.

2. Pathak SM, Schaefer KJ, Jamei M, Turner DB. Biopharmaceutic IVIVE-mechanistic modeling of single- and two-phase in vitro experiments to obtain drug-specific parameters for incorporation into PBPK models. J Pharm Sci. 2019;108(4):1604–18. https://doi.org/10.1016/j.xphs.2018.11.034.

3. Mudie DM, Shi Y, Ping H, Gao P, Amidon GL, Amidon GE. Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus. Biopharm Drug Dispos. 2012;33(7):378–402. https://doi.org/10.1002/bdd.1803.

4. Cristofoletti R, Hens B, Patel N, Esteban VV, Schmidt S, Dressman J. Integrating drug- and formulation-related properties with gastrointestinal tract variability using a product-specific particle size approach: Case example ibuprofen. J Pharm Sci. 2019;108(12):3842–7. https://doi.org/10.1016/j.xphs.2019.09.012.

5. Yamazaki S, Evers R, De Zwart L. Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition. CPT Pharmacometrics Syst Pharmacol. 2022;11(1):55–67. https://doi.org/10.1002/psp4.12733.

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