Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies
Author:
Affiliation:
1. Department of Drug Metabolism and Pharmacokinetics, Genentech Inc.; South San Francisco; USA
2. Department of Clinical Pharmacology, Genentech Inc.; South San Francisco; USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
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5. Have physiologically-based pharmacokinetic models delivered?;Edginton;Expert Opin Drug Metab Toxicol,2011
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