Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine-Reference-Cited by-同舟云学术

Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine

Published:2014-07-18 Issue:1 Volume:32 Page:74-90
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Heikkinen Aki T.,Friedlein Arno,Matondo Mariette,Hatley Oliver J. D.,Petsalo Aleksanteri,Juvonen Risto,Galetin Aleksandra,Rostami-Hodjegan Amin,Aebersold Ruedi,Lamerz Jens,Dunkley Tom,Cutler Paul,Parrott Neil

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-014-1446-8.pdf

Reference69 articles.

1. Sakamoto A, Matsumaru T, Ishiguro N, et al. Reliability and robustness of simultaneous absolute quantification of drug transporters, cytochrome P450 enzymes, and Udp-glucuronosyltransferases in human liver tissue by multiplexed MRM/selected reaction monitoring mode tandem mass spectrometry with nano-liquid chromatography. J Pharm Sci. 2011;100:4037–43.

2. Miliotis T, Ali L, Palm JE, et al. Development of a Highly Sensitive Method using LC-MRM to Quantify Membrane P-glycoprotein in Biological Matrices and Relationship to Transport Function. Drug Metab Dispos. 2011;39:2440–9.

3. Harbourt DE, Fallon JK, Ito S, et al. Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography–tandem mass spectrometry. Anal Chem. 2011;84:98–105.

4. Harwood MD, Neuhoff S, Carlson GL, Warhurst G, Rostami-Hodjegan A. Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption. Biopharm Drug Dispos. 2013;34:2–28.

5. Rostami-Hodjegan A, Tucker GT. Simulation and prediction of in vivo drug metabolism in human populations from in vitro data. Nat Rev. 2007;6:140–8.

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