Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Reference39 articles.
1. Lipinski CA. Drug-like properties and the causes of poor solubility and poor permeability. Journal of Pharmacological & Toxicological Methods. 2000;44:235–49.
2. Lipinski CA. Poor aqueous solubility -an industry wide problem in ADME screening. American Pharmaceutical Review. 2002;5:82–5.
3. C.A. Lipinski. Physicochemical properties and the discovery of orally active drugs: technical and people issues. Molecular Informatics: Confronting Complexity, May 13th - 16th 2002, Bozen, Italy (2003).
4. Brouwers J, Brewster ME, Augustijns P. Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? J Pharm Sci. 2009;98:2549–72.
5. Liu C, Chen Z, Chen Y, Lu J, Li Y, Wang S, et al. Improving oral bioavailability of Sorafenib by optimizing the "spring" and "parachute" based on molecular interaction mechanisms. Mol Pharm. 2015;13:599.
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