Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design
Author:
Funder
Foundation for the National Institutes of Health
BrightFocus Foundation
Publisher
Springer Science and Business Media LLC
Subject
Geriatrics and Gerontology,Aging
Link
https://link.springer.com/content/pdf/10.1007/s11357-023-00830-5.pdf
Reference58 articles.
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3. Prata LGL, Ovsyannikova IG, Tchkonia T, Kirkland JL, editors. Senescent cell clearance by the immune system: emerging therapeutic opportunities. Seminars in immunology; 2018: Elsevier.
4. Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M. The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 2015;14(4):644–58.
5. Xu J, Zhou L, Liu Y. Cellular senescence in kidney fibrosis: pathologic significance and therapeutic strategies. Front Pharmacol. 2020;11:1898.
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