Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00558224.pdf
Reference33 articles.
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4. Birgersson C, Morgan ET, Jörnvall H, von Bahr C (1986) Purification of a desmethylimipramine and debrisoquin hydroxylating cytochrome P-450 from human liver. Biochem Pharmacol 35: 3165?3166
5. Bertilsson L, Aberg-Wistedt A (1983) The debrisoquin hydroxylation test predicts steady-state plasma levels of desipramine. Br J Clin Pharmacol 15: 388?390
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