GR 38032F (Ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man

Author:

Talley N. J.,Phillips S. F.,Haddad A.,Miller L. J.,Twomey C.,Zinsmeister A. R.,MacCarty R. L.,Ciociola A.

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology,Physiology

Reference22 articles.

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2. Gaddum JH, Picarelli ZP: Two kinds of tryptamine receptor. Br J Pharmcol 12:323?328, 1957

3. Peroutka SJ, Snyder SH: Multiple serotonin receptors: Differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol. Mol Pharmacol 16:687?699, 1979

4. Engel G, Hoyer P, Kalkmon HO, Wick MD: Pharmacological similarity between the 5HT-D-receptor on the guinea pig ileum and the 5HT2 binding site. Br J Pharmacol 84:106P, 1985

5. Kilpatrick GJ, Jones BJ, Tyers MB: Identification and distribution of 5HT3 receptors in rat brain using radioligand binding. Nature 330:746?748, 1987

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