Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability
Author:
Funder
National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s12192-021-01191-8.pdf
Reference66 articles.
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2. Aguzzi A, Falsig J (2012) Prion propagation, toxicity and degradation. Nat Neurosci 15(7):936–939. https://doi.org/10.1038/nn.3120
3. Andre R, Tabrizi SJ (2012) Misfolded PrP and a novel mechanism of proteasome inhibition. Prion 6(1):32–36. https://doi.org/10.4161/pri.6.1.18272
4. Astolfi A, Spagnolli G, Biasini E, Barreca ML (2020) The compelling demand for an effective PrPC-directed therapy against prion diseases. ACS Med Chem Lett 8–12. https://doi.org/10.1021/acsmedchemlett.0c00528
5. Astor MT, Kamiya E, Sporn ZA, Berger SE, Hines JK (2018) Variant-specific and reciprocal Hsp40 functions in Hsp104-mediated prion elimination. Mol Microbiol 109(1):41–62. https://doi.org/10.1111/mmi.13966
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