Synthesis and structure–activity relationship of acylthiourea derivatives as inhibitors of microsomal epoxide hydrolase-Reference-Cited by-同舟云学术

Synthesis and structure–activity relationship of acylthiourea derivatives as inhibitors of microsomal epoxide hydrolase

Published:2012-01-05 Issue:12 Volume:21 Page:4214-4218
ISSN:1054-2523
Container-title:Medicinal Chemistry Research
language:en
Short-container-title:Med Chem Res

Author:

Shen Wei,Fang Yi,Tong Aifei,Zhu Qing

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Link

http://link.springer.com/content/pdf/10.1007/s00044-011-9953-1.pdf

Reference18 articles.

1. Baxter SW, Choong DYH, Campbell IG (2002) Microsomal epoxide hydrolase polymorphism and susceptibility to ovarian cancer. Cancer Lett 177:75–81

2. Benhamou S, Reinikainen M, Bouchary C, Dayer P, Hirvonen A (1998) Association between lung cancer and microsomal epoxide hydrolase genotypes. Cancer Res 58:5291–5293

3. Hamouchene H, Arlt VM, Giddings I et al (2011) Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene. BMC Gen 12:333. doi: 10.1186/1471-2164-12-333

4. Lewis DF, Lake BG, Bird MG (2005) Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity. Toxicol In Vitro 19:517–522

5. Me′sange F, Sebbar M, Kedjouar B et al (1998) Microsomal epoxide hydrolase of rat liver is a subunit of the anti-oestrogen-binding site. Biochem J 334:107–112

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