An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles-Reference-Cited by-同舟云学术

An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles

Published:2022-09-22 Issue:12 Volume:31 Page:2132-2151
ISSN:1054-2523
Container-title:Medicinal Chemistry Research
language:en
Short-container-title:Med Chem Res

Author:

Mphahlele Malose J.^ORCID,Magwaza Nontokozo M.,More Garland K.,Gildenhuys Samantha

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Link

https://link.springer.com/content/pdf/10.1007/s00044-022-02972-1.pdf

Reference52 articles.

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2. Ghabi A, Brahmi J, Almiderej F, Messaaoudi S, Vidal S, Kadri A, et al. Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors. Bioorg Chem. 2020;98:103713. https://doi.org/10.1016/j.bioorg.2020.103713.

3. Alam F, Shafique Z, Amjad ST, Bin Asad MHH. Enzymes inhibitors from natural sources with antidiabetic activity: A review. Phytother Res. 2019;33:41–54. https://doi.org/10.1002/ptr.6211.

4. Imran S, Taha M, Selvaraj M, Ismail NH, Chigurupati S, Mohammad JI. Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor. Bioorg Chem. 2017;73:121–7. https://doi.org/10.1016/j.bioorg.2017.06.007.

5. Aispuro-Pérez A, López-Ávalos J, García-Páez F, Montes-Avila J, Picos Corrales LA, Ochoa-Terán A, et al. Synthesis and molecular docking studies of imines as α-glucosidase and α-amylase inhibitors. Bioorg Chem. 2020;94:103491. https://doi.org/10.1016/j.bioorg.2019.103491.

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