Glucose-dependent downregulation of glucagon gene expression mediated by selective interactions between ALX3 and PAX6 in mouse alpha cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00125-015-3849-4.pdf
Reference49 articles.
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3. Dunning BE, Gerich JE (2007) The role of α-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications. Endocr Rev 28:253–283
4. Unger RH, Cherrington AD (2012) Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover. J Clin Invest 122:4–12
5. Leibiger B, Moede T, Muhandiramlage TP et al (2012) Glucagon regulates its own synthesis by autocrine signaling. Proc Natl Acad Sci U S A 109:20925–20930
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