Prevalent role of the insulin receptor isoform A in the regulation of hepatic glycogen metabolism in hepatocytes and in mice-Reference-Cited by-同舟云学术

Prevalent role of the insulin receptor isoform A in the regulation of hepatic glycogen metabolism in hepatocytes and in mice

Published:2016-09-07 Issue:12 Volume:59 Page:2702-2710
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Diaz-Castroverde Sabela,Baos Selene,Luque María,Di Scala Marianna,González-Aseguinolaza Gloria,Gómez-Hernández Almudena,Beneit Nuria,Escribano Oscar,Benito Manuel

Funder

Ministerio de Ciencia e Innovación

Instituto de Salud Carlos III

Consorcio MOIR. Comunidad de Madrid

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00125-016-4088-z.pdf

Reference29 articles.

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2. Leibiger B, Leibiger IB, Moede T et al (2001) Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells. Mol Cell 7:559–570

3. Benyoucef S, Surinya KH, Hadaschik D, Siddle K (2007) Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation. Biochem J 403:603–613

4. Ward CW, Lawrence MC (2009) Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor. Bioessays 31:422–434

5. Whittaker J, Sørensen H, Gadsbøll VL, Hinrichsen J (2002) Comparison of the functional insulin binding epitopes of the A and B isoforms of the insulin receptor. J Biol Chem 277:47380–47384

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