Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate metabolism-Reference-Cited by-同舟云学术

Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate metabolism

Published:2012-12-14 Issue:5 Volume:405 Page:1695-1704
ISSN:1618-2642
Container-title:Analytical and Bioanalytical Chemistry
language:en
Short-container-title:Anal Bioanal Chem

Author:

Hu Zhe-Yi,Parker Robert B.,Herring Vanessa L.,Laizure S. Casey

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Link

http://link.springer.com/content/pdf/10.1007/s00216-012-6576-4.pdf

Reference24 articles.

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2. Blech S, Ebner T, Ludwig-Schwellinger E, Stangier J, Roth W (2008) The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab Dispos 36(2):386–399

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4. Sato Y, Miyashita A, Iwatsubo T, Usui T (2012) Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry. Drug Metab Dispos 40(7):1389–1396

5. Delavenne X, Moracchini J, Laporte S, Mismetti P, Basset T (2012) UPLC MS/MS assay for routine quantification of dabigatran—a direct thrombin inhibitor—in human plasma. J Pharm Biomed Anal 58:152–156

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