On-line electrochemistry–bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors-Reference-Cited by-同舟云学术

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On-line electrochemistry–bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors

Published:2012-01-08 Issue:2 Volume:403 Page:367-375
ISSN:1618-2642
Container-title:Analytical and Bioanalytical Chemistry
language:en
Short-container-title:Anal Bioanal Chem

Author:

Falck David,de Vlieger Jon S. B.,Giera Martin,Honing Maarten,Irth Hubertus,Niessen Wilfried M. A.,Kool Jeroen

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Link

http://link.springer.com/content/pdf/10.1007/s00216-011-5663-2

Reference24 articles.

1. Nouri-Nigjeh E, Bischoff R, Bruins AP, Permentier HP (2011) Electrochemistry in the mimicry of oxidative drug metabolism by cytochrome p450s. Curr Drug Metab 12(4):359–371

2. Thevis M, Lohmann W, Schrader Y, Kohler M, Bornatsch W, Karst U, Schanzer W (2008) Use of an electrochemically synthesised metabolite of a selective androgen receptor modulator for mass spectrometry-based sports drug testing. Eur J Mass Spectrom 14(3):163–170

3. Madsen KG, Gronberg G, Skonberg C, Jurva U, Hansen SH, Olsen J (2008) Electrochemical oxidation of troglitazone: identification and characterization of the major reactive metabolite in liver microsomes. Chem Res Toxicol 21(10):2035–2041

4. Hillard EA, de Abreu FC, Ferreira DCM, Jaouen G, Goulart MOF, Amatore C (2008) Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds. Chem Commun (Cambridge, U K) 23(23):2612–2628

5. Baumann A, Karst U (2010) Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications. Expert Opin Drug Metab Toxicol 6(6):715–731

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