Quantification of 3-MCPD and its mercapturic metabolite in human urine: validation of an LC–MS–MS method and its application in the general population

Author:

Andreoli Roberta,Cirlini Martina,Mutti Antonio

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Reference9 articles.

1. Baer I, de la Calle B, Taylor P (2010) 3-MCPD in food other than soy sauce or hydrolysed vegetable protein (HVP). Anal Bioanal Chem 396:443–456

2. SCF (Scientific Committee on Food), Opinion on 3-mono-chloro-propane-1,2-diol (3-MCPD), Updating the SCF opinion of 1994 adopted on 30 May 2001. European Commission, Brussels, 2001, http://ec.europa.eu/foof/fs/sc/scf/out91_en.pdf (accessed October 2010)

3. JECFA (Joint FAO/WHO Expert Committee on Food Additives). 3-Chloro-1,2-propanediol. WHO Food Add. Ser. 48, 2002, pp 401–432, WHO, Geneva. http://www.inchem.org/documents/jecfa/jecmono/v48je18.htm (accessed October 2010)

4. Silhánková L, Smíd F, Cerná M, Davídek J, Velísek J (1982) Mutagenicity of glycerol chlorohydrines and of their esters with higher fatty acids present in protein hydrolysates. Mutat Res 103(1):77–81

5. El Ramy R, OuldElhkim M, Lezmi S, Poul JM (2007) Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and beta-chlorolactic acid, using the single cell gel/comet assay. Food Chem Toxicol 45(1):41–48

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