Inhibition of ARNT severely compromises endothelial cell viability and function in response to moderate hypoxia-Reference-Cited by-同舟云学术

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Inhibition of ARNT severely compromises endothelial cell viability and function in response to moderate hypoxia

Published:2012-04-07 Issue:3 Volume:15 Page:409-420
ISSN:0969-6970
Container-title:Angiogenesis
language:en
Short-container-title:Angiogenesis

Author:

Han Yu,Yang Ke,Proweller Aaron,Zhou Guangjin,Jain Mukesh K.,Ramirez-Bergeron Diana L.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Clinical Biochemistry,Physiology

Link

http://link.springer.com/content/pdf/10.1007/s10456-012-9269-x.pdf

Reference62 articles.

1. Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG Jr (1998) Regulation of hypoxia-inducible mrnas by the von hippel-lindau tumor suppressor protein requires binding to complexes containing elongins b/c and cul2. Mol Cell Biol 18(2):732–741

2. Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH (2000) Hypoxia inducible factor-alpha binding and ubiquitylation by the von hippel-lindau tumor suppressor protein. J Biol Chem 275(33):25733–25741

3. Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O’Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ (2001) C. elegans egl-9 and mammalian homologs define a family of dioxygenases that regulate hif by prolyl hydroxylation. Cell 107(1):43–54

4. Wang GL, Jiang BH, Rue EA, Semenza GL (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-pas heterodimer regulated by cellular o2 tension. Proc Natl Acad Sci USA 92(12):5510–5514

5. Ramirez-Bergeron DL, Runge A, Adelman DM, Gohil M, Simon MC (2006) Hif-dependent hematopoietic factors regulate the development of the embryonic vasculature. Dev Cell 11(1):81–92

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