Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein-Reference-Cited by-同舟云学术

Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

Published:2000-08 Issue:33 Volume:275 Page:25733-25741
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Cockman Matthew E.,Masson Norma,Mole David R.,Jaakkola Panu,Chang Gin-Wen,Clifford Steven C.,Maher Eamonn R.,Pugh Christopher W.,Ratcliffe Peter J.,Maxwell Patrick H.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference34 articles.

1. The VHL tumour-suppressor gene paradigm

2. Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.

3. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene.

4. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

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