Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis-Reference-Cited by-同舟云学术

Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis

Published:2020-01-10 Issue:1 Volume:7 Page:12-21
ISSN:2196-3002
Container-title:Current Oral Health Reports
language:en
Short-container-title:Curr Oral Health Rep

Author:

Hajishengallis George,Diaz Patricia I.

Publisher

Springer Science and Business Media LLC

Subject

Immunology and Microbiology (miscellaneous),Oral Surgery,Surgery

Link

http://link.springer.com/content/pdf/10.1007/s40496-020-00249-3.pdf

Reference135 articles.

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2. Diaz PI, Hoare A, Hong BY. Subgingival microbiome shifts and community dynamics in periodontal diseases. Journal of the California Dental Association. 2016;44(7):421–35.

3. Kebschull M, Demmer RT, Papapanou PN. “Gum bug leave my heart alone”: epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis. J Dent Res. 2010;89:879–902.

4. •• Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, et al. Porphyromonas gingivalis in Alzheimer’s disease brains: evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019;5(1):eaau3333 This study identified the presence of gingipains from the keystone pathogenPorphyromonas gingivalisin the brain of Alzheimer’s patients, and showed that inhibition of gingipains by small-molecule inhibitors reduced theP. gingivalisload in a preclinical brain infection model.

5. Potempa J, Mydel P, Koziel J. The case for periodontitis in the pathogenesis of rheumatoid arthritis. Nat Rev Rheumatol. 2017;13(10):606–20.

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