Characterization of the Pharmacokinetics and Mass Balance of a Single Oral Dose of Trofinetide in Healthy Male Subjects
Author:
Funder
ACADIA Pharmaceuticals
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s40261-023-01322-2.pdf
Reference19 articles.
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2. Buchanan CB, Stallworth JL, Scott AE, Glaze DG, Lane JB, Skinner SA, et al. Behavioral profiles in Rett syndrome: data from the natural history study. Brain Dev. 2019;41:123–34. https://doi.org/10.1016/j.braindev.2018.08.008.
3. Lane JB, Lee H-S, Smith LW, Cheng P, Percy AK, Glaze DG, et al. Clinical severity and quality of life in children and adolescents with Rett syndrome. Neurology. 2011;77:1812–8. https://doi.org/10.1212/WNL.0b013e3182377dd2.
4. Bickerdike MJ, Thomas GB, Batchelor DC, Sirimanne ES, Leong W, Lin H, et al. NNZ-2566: a Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke. J Neurol Sci. 2009;278:85–90. https://doi.org/10.1016/j.jns.2008.12.003.
5. Collins BE, Neul JL. Trofinetide. Glycine-proline-glutamate (GPE) analogue, treatment of Rett syndrome, treatment of fragile X syndrome. Drugs Fut. 2021;46:29. https://doi.org/10.1358/dof.2021.46.1.3208246.
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