NNZ-2566: A Gly–Pro–Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke

Author:

Bickerdike Michael J.,Thomas Gregory B.,Batchelor David C.,Sirimanne Ernest S.,Leong Wing,Lin Hai,Sieg Frank,Wen Jingyuan,Brimble Margaret A.,Harris Paul W.,Gluckman Peter D.

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology

Reference35 articles.

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2. Identification of Gly–Pro–Glu (GPE), the aminoterminal tripeptide of insulin-like growth factor 1 which is truncated in brain, as a novel neuroactive peptide;Sara;Biochem Biophys Res Commun,1989

3. Effects of IGF-1, truncated IGF-1 and the tripeptide Gly–Pro–Glu on acetylcholine release from parietal cortex of rat brain;Nilsson-Hakansson;Neuroreport,1993

4. Neuroprotective effects of Gly–Pro–Glu, the N-terminal tripeptide of IGF-1, in the hippocampus in vitro;Saura;Neuroreport,1990

5. The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity;Alonso De Diego;Bioorg Med Chem Lett,2006

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