Mature and immature ovarian teratomas share methylation profiles of imprinted genes: a MS-MLPA analysis
Author:
Funder
JSPS KAKENHI
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,General Medicine,Pathology and Forensic Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00428-023-03491-z.pdf
Reference18 articles.
1. Prat J (2014) Ovarian germ cell tumors. In: Mutter GL, Prat J (eds) Pathology of the female reproductive tract, 3rd edn. Churchill Livingstone, London, pp 670–693
2. Snir OL, DeJoseph M, Wong S, Buza N, Hui P (2017) Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis. Mod Pathol 30:1467–1475
3. Heskett MB, Sanborn JZ, Boniface C et al (2020) Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components. Mod Pathol 33:1193–1206
4. Jung SH, Park HC, Choi YJ, Song SY, Chung YJ, Lee SH (2022) Molecular genetic evidence supporting diverse histogenetic origins of germ cell tumors. J Pathol 256:38–49
5. Kato N, Kamataki A, Kurotaki H (2021) Methylation profiles of imprinted genes are distinct between mature ovarian teratoma, complete hydatidiform mole, and extragonadal mature teratoma. Mod Pathol 34:502–507
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1. Immature Teratoma: Diagnosis and Management—A Review of the Literature;Diagnostics;2023-04-23
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