Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its active metabolites

Author:

Lee Hye-In,Byeon Ji-Young,Kim Young-Hoon,Lee Choong-Min,Choi Chang-Ik,Jang Choon-Gon,Bae Jung-Woo,Lee Yun Jeong,Lee Seok-Yong

Funder

National Research Foundation of Korea

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference39 articles.

1. Kimura Y, Tani T, Kanbe T et al (1985) Effect of cilostazol on platelet aggregation and experimental thrombosis. Arzneimittelforschung 35:1144–1149

2. Uchikawa T, Murakami T, Furukawa H (1992) Effects of the anti-platelet agent cilostazol on peripheral vascular disease in patients with diabetes mellitus. Arzneimittelforschung 42:322–324

3. Dawson DL, Cutler BS, Meissner MH et al (1998) Cilostazol has beneficial effects in treatment of intermittent claudication: results from a multicenter, randomized, prospective, double-blind trial. Circulation 98:678–686

4. Pletal [label]. Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan, 2007 < http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020863s021lbl.pdf>

5. Bramer SL, Forbes WP (1999) Effect of hepatic impairment on the pharmacokinetics of a single dose of cilostazol. Clin Pharmacokinet 37:25–32

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